Copper Sulfate







Product Name:   Copper Sulfate

Formula:             CuSO4 · 5H2O

Supplier:             ESPI Metals

                            1050 Benson Way

                            Ashland, OR 97520

Telephone:          800-638-2581

Fax:                     541-488-8313

Email:                  This email address is being protected from spambots. You need JavaScript enabled to view it.

Emergency:         Infotrac 800-535-5053 (US) or 352-323-3500 (24 hour)

Recommended Uses:  Scientific Research




GHS Classification (29 CFR 1910.1200): Acute toxicity - oral, category 4, Skin corrosion/irritation, category 2, Eye damage/irritation, category 2A.

GHS Label Elements:


Signal Word: Warning

Hazard Statements: H302 Harmful if swallowed, H315 Causes skin irritation, H319 Causes serious eye irritation.

Precautionary Statements: P260 Do not breath dust or vapors, P264 Wash skin thoroughly after handling, P270 Do not eat, drink or smoke when using this product, P280 Wear protective gloves/protective clothing/eye protection/face protection P301+P312+P330 IF SWALLOWED: Rinse mouth. Call a POISON CENTER or doctor/physician if you feel unwell, P302+P352 IF ON SKIN: wash with plenty of soap and water, P332+P313 IF SKIN irritation occurs: Get medical advice/attention, P305+P351+P338 IF IN EYES: rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing, P337+P313 IF eye irritation persists: Get medical advice/attention, P362+P364 Take off contaminated clothing and wash it before reuse, P501 Dispose of contents/container in accordance with local, state or federal regulations.




Ingredient:    Copper (II) Sulfate Pentahydrate

CAS#:             7758-99-8

%:                  100

EC#:               231-847-6

Common Names and Synonyms: Cupric sulfate pentahydrate; blue vitriol; copper(II) salt (1:1) pentahydrate.




General Measures: Remove patient from area of exposure.

INHALATION: Remove to fresh air, keep warm and quiet, give oxygen if breathing is difficult. Seek immediate medical attention.

INGESTION: Rinse mouth with water. Do not induce vomiting. Seek immediate medical attention. Never induce vomiting or give anything by mouth to an unconscious person.

SKIN: Remove contaminated clothing, brush material off skin, wash affected area with soap and water. Seek medical attention. Wash contaminated clothing before reuse.

EYES: Flush eyes with lukewarm water, including under upper and lower eyelids, for at least 15 minutes. Seek medical attention.

Most Important Symptoms/Effects, Acute and Delayed: May cause allergy or asthma symptoms or breathing difficulties if inhaled. May cause allergic skin reaction. See section 11 for more information.

Indication of Immediate Medical Attention and Special Treatment: No other relevant information available.




Extinguishing Media: Use suitable extinguishing agent for surrounding materials and type of fire.

Unsuitable Extinguishing Media: No information available.

Specific Hazards Arising from the Material: May release toxic fumes if involved in a fire.

Special Protective Equipment and Precautions for Firefighters: Wear full face, self-contained breathing apparatus and full protective clothing.




Personal Precautions, Protective Equipment, and Emergency Procedures: Wear appropriate respiratory and protective equipment specified in section 8. Isolate spill area and provide ventilation. Avoid breathing dust or fume. Avoid contact with skin and eyes. Eliminate all sources of ignition.

Methods and Materials for Containment and Cleaning Up: Avoid raising dust. Scoop or vacuum up using a vacuum system equipped with a HEPA filter. Place in properly labeled closed containers.

Environmental Precautions: Do not allow to enter drains or to be released to the environment.




Precautions for Safe Handling: Handle in an enclosed, controlled process. Avoid creating dust. Avoid breathing dust or fumes. Provide adequate ventilation if dusts are created. Avoid contact with skin and eyes. Wash thoroughly before eating or smoking. See section 8 for information on personal protection equipment.

Conditions for Safe Storage: Store in a cool, dry area. Store material tightly sealed in properly labeled containers. Protect from moisture. See section 10 for more information on incompatible materials.




Exposure Limits:                      OSHA/PEL:                              ACGIH/TLV:

Copper Sulfate                            No exposure limit established     No exposure limit established

Copper dusts and mists (as Cu)   1 mg/m3                                   1 mg/m3

Engineering Controls: Handle in a controlled, enclosed environment. Whenever possible the use of local exhaust ventilation or other engineering controls is the preferred method of controlling exposure to airborne dust and fume to meet established occupational exposure limits. Use good housekeeping and sanitation practices. Do not use tobacco or food in work area. Wash thoroughly before eating or smoking. Do not blow dust off clothing or skin with compressed air.

Individual Protection Measures, Such as Personal Protective Equipment:

   Respiratory Protection: NIOSH approved respirator.

   Eye Protection: Safety glasses

   Skin Protection: Impermeable gloves, protective work clothing as necessary.





Form:                 Powder

Color:                 Blue

Odor:                  No data

Odor Threshold: Not determined

pH:                                              N/A

Melting Point:                             No data

Boiling Point:                              No data

Flash Point:                                N/A

Evaporation Rate:                      N/A

Flammability:                             No data

Upper Flammable Limit:            No data

Lower Flammable Limit:            No data

Vapor Pressure:                          No data

Vapor Density:                            N/A

Relative Density (Specific Gravity):     2.284 g/cc

Solubility in H2O:                         31.6 g/100 ml @ 0 oC

Partition Coefficient (n-octanol/water):   Not determined

Autoignition Temperature:         No data

Decomposition Temperature:     No data

Viscosity:                                     N/A




Reactivity: No specific test data available.

Chemical Stability: Stable under recommended storage conditions.

Possibility of Hazardous Reactions: Reacts violently with hydroxylamine, magnesium.

Conditions to Avoid: Hygroscopic, protect from moisture.

Incompatible Materials: Powdered metals, hydroxylamine.

Hazardous Decomposition Products: Copper oxides, sulfur oxides.




Likely Routes of Exposure: Inhalation, skin and eyes.

Symptoms of Exposure: May cause chills, flushing, fatigue, muscle and stomach aches, dyspnea, and nausea if fumes are inhaled. Dusts may irritate skin and eyes.

Acute and Chronic Effects:

Copper Compounds: In general the soluble ionized salts of copper are much more toxic than the insoluble or slightly dissociated compounds. The lethal dose of any copper salt varies widely (from less than 1 g to several ounces in adults). Systemic toxic effects of copper include widespread capillary damage, kidney and liver injury, and central nervous excitation followed by depression. Jaundice and pain over the liver have been reported in acute human poisonings. Copper is mainly absorbed through the gastrointestinal tract. All other intakes of copper (inhalation and dermal) are insignificant in comparison to the oral route.

Sulfates: Sulfates have variable toxicity. In general the toxic properties of substances containing the sulfate radical is that of the material (cation) with which the sulfate (anion) is combined. Copper sulfate may be acutely toxic and corrosive, while iron sulfate is regarded as an irritant and sodium sulfate is considered non-toxic and non-irritating to skin and mucous membranes.

Acute Toxicity: LD50 oral - rat - 960 mg/kg

Carcinogenicity: NTP: Not identified as carcinogenic   IARC: Not identified as carcinogenic

To the best of our knowledge the chemical, physical and toxicological characteristics of the substance are not fully known.




Ecotoxicity: LC50 Pimephales promelas (fathead minnow) 0.838 mg/L - static

Persistence and Degradability: No data

Bioaccumulative Potential: No data

Mobility in Soil: No data

Other Adverse Effects: Do not allow material to be released to the environment. No further relevant information available.




Waste Disposal Method:

Product: Dispose of in accordance with Federal, State and Local regulations.

Packaging: Dispose of in accordance with Federal, State and Local regulations.




UN Number:                           UN3077

UN Proper Shipping Name:   Environmentally hazardous substance, solid, n.o.s. (Copper sulfate pentahydrate)

Transport Hazard Class:       9

Packing Group:                      III

Marine Pollutant:                   Yes




TSCA Listed: No

DSL Listed: No

Regulation (EC) No 1272/2008 (CLP): Acute toxicity - oral, category 4, Skin corrosion/irritation, category 2, Eye damage/irritation, category 2A, Hazardous to the aquatic environment - acute hazard, category 1, Hazardous to the aquatic environment - chronic hazard, category 1.

WHMIS 2015 Classification: Acute toxicity, Skin corrosion/irritation, Serious eye damage/eye irritation.

HMIS Ratings: Health: 2     Flammability: 0     Physical: 0

NFPA Ratings: Health: 2     Flammability: 0     Instability: 0

Chemical Safety Assessment: A chemical safety assessment has not been carried out.




The information contained in this document is based on the state of our knowledge at the time of publication and is believed to be correct, but does not purport to be all inclusive and shall be used only as a guide. ESPI Metals makes no representation, warranty, or guarantee of any kind with respect to the information contained in this document or any use of the product based on this information. ESPI Metals shall not be held liable for any damages resulting from handling or from contact with the above product. Users should satisfy themselves that they have all current data relevant to their particular use.


Prepared by:             ESPI Metals

Revised/Reviewed:   February 2017